Are anthraquinones phytochemicals?

Anthraquinones, as the name implies, are phytochemicals based on anthracene (three benzene rings joined together).

What is are the pharmaceutical application of anthraquinones?

Besides their utilization as colorants, anthraquinone derivatives have been used since centuries for medical applications, for example, as laxatives and antimicrobial and antiinflammatory agents. Current therapeutic indications include constipation, arthritis, multiple sclerosis, and cancer.

Does anthraquinone cause cancer?

Anthraquinones are known to be mutagenic and may be carcinogenic in experimental systems but danthron is not a proven carcinogen in man. The association of danthron and a rare bowel cancer in one case cannot prove a causative link. However, collection of further data seems advisable.

What is are the usual solvent used for the extraction of anthraquinones?

Twelve extraction solvents (water, 20% ethanol(aq), 40% ethanol(aq), 60% ethanol(aq), 70% ethanol(aq), 80% ethanol(aq), ethanol, 70% methanol(aq), methanol, 70% acetone(aq), acetone and dichloromethane) were used for the extraction of anthraquinones (yellow dyes) from Japanese knotweed rhizomes.

Can anthraquinones be absorbed through the skin?

* Anthraquinone can affect you when breathed in and may be absorbed through the skin.

What foods contain anthraquinones?

Introduction. Anthraquinones (AQs) are found in rhubarb root, Senna leaf and pod, Cascara, Buckhorn, and Aloe, and they are widely used in laxative preparations. AQ laxatives include physcion, chrysophanol, aloe-emodin, rhein, and sennosides.

Can rhubarb cause cancer?

Preclinical studies have shown that rhubarb has toxic effects on the liver and kidneys and is associated with cancer risk. Emodin, the main causative agent of rhubarb hepatotoxicity [96], can cause apoptosis in normal human L02 cells and increase the expression of liver injury markers [97].

What is the structure of 2 Ethylanthraquinol?


How is anthraquinone made?

It is prepared commercially by oxidation of anthracene or condensation of benzene and phthalic anhydride, followed by dehydration of the condensation product. The anthraquinones occur widely in plants but in only a few animals.

What herbs cause melanosis coli?

The exact composition of so called”narural, herbal, safe” laxatives should be ascertained: besides cascara sagrada other herbs such as Aloe vera and Senna (Swiss Kriss) may contain chemicals which can cause melanosis coli & other serious side effects.

Are there any safety concerns with anthraquinones laxatives?

However, the presence of the quinone moiety in the structure of anthraquinones raises safety concerns, and anthraquinone laxatives have therefore been under critical reassessment. This review article provides an overview of the chemistry, biology, and toxicology of anthraquinones focusing on their application as drugs.

Are there any natural anthraquinones that are antimicrobial?

Considering the great structural diversity and variations in chemical composition, numerous antimicrobial in vitro and/or in vivo activities of natural and synthetic anthraquinones have been reported, however there has been limited research related to the structural-functional relationship of these compounds.

What kind of anthraquinones are found in Cassia?

Species of Cassia are rich source of anthraquinones which are wellknown as natural dyes, and are gaining importance in recent… CONTINUE READING Johanna Duval, V. Pecher, M. Poujol, É.

What kind of core does an anthraquinone have?

Anthraquinones and their derivatives are a class of aromatic compounds with a 9,10-dioxoanthracene core.