What is a drug-coated balloon angioplasty?

Drug-Coated Balloon (DCB) angioplasty is similar to plain old balloon angioplasty procedurally, but there is the addition of an anti-proliferative medication coating the balloon, as well as an excipient to aid in drug transfer, which may help prevent restenosis.

What is drug-coated balloon used for?

Drug-coated balloon (DCB) is a novel device for percutaneous coronary intervention (PCI), which has demonstrated favorable outcome due to its peculiar characteristic of a high-concentration, rapid local delivery of an antirestenotic drug without the use of a durable polymer or metal stent.

How do drug-coated balloons work?

All the balloons are a little bit different in terms of how they work, but the primary mechanism is that the balloon is coated with paclitaxel and a carrier molecule (or excipient), which basically allows the drug to come off the balloon and be delivered into the vessel wall where it sticks around long enough to have …

What is drug-eluting balloon?

A drug-eluting balloon is a non-stent technology in which the effective homogenous delivery of anti-proliferative drugs is processed by the vessel wall through an inflated balloon.

What is the procedure for balloon angioplasty?

A specially designed catheter with a tiny balloon is carefully guided through the artery to the blockage, then inflated to widen the opening and increase blood flow to the heart. A stent is often placed during the procedure, to keep the artery open after the balloon is deflated and removed.

What medication is in drug eluting stent?

This is the TAXUS Express2 Paclitaxel-Eluting Coronary Stent System, which releases paclitaxel. A drug-eluting stent (DES) is a peripheral or coronary stent (a scaffold) placed into narrowed, diseased peripheral or coronary arteries that slowly releases a drug to block cell proliferation.

What medication is in drug-eluting stent?

How long does a drug eluting stent work?

If you get a drug-eluting stent, you will probably take both of these medicines for at least 6 months. If you get a bare-metal stent, you may take both medicines for at least 1 month. If you had a heart attack, you may take both medicines for at least 1 year.

What are the disadvantages of balloon angioplasty?

Risks: The insertion site may bleed or become infected. The artery may become blocked again (restenosis). The artery may tear (artery dissection).

What are the disadvantages of angioplasty?

The disadvantages of coronary angioplasty are: The procedure is not suitable if multiple blood vessels are affected or the artery is narrowed at multiple locations. It cannot be used in arteries that cannot be reached by the catheter. It may not be effective against very hard atherosclerotic plaques.

What is the life of a medicated stent?

What is the typical lifespan of a stent? Stents are small tubes inserted into your body to reopen a narrowed artery. They are made to be permanent — once a stent is placed, it’s there to stay. In cases when a stented coronary artery does re-narrow, it usually happens within 1 to 6 months after placement.

What is the drug coating on a PTA catheter?

The drug component, referred to as the FreePac™ drug coating, consists of the drug paclitaxel and the excipient urea. The device component physically dilates the vessel lumen by PTA, and the drug is intended to reduce the proliferative response that is associated with restenosis.

What is the drug coating on the pact Admiral balloon catheter?

2.0 Product Description The IN.PACT Admiral paclitaxel-coated PTA balloon catheter is an over-the-wire [OTW] balloon catheter with a drug-coated balloon at the distal tip. The drug component, referred to as the FreePac™ drug coating, consists of the drug paclitaxel and the excipient urea.

What kind of balloon catheter is used for AV?

The IN.PACT AV Paclitaxel-coated Percutaneous Transluminal Angioplasty (PTA) Balloon Catheter (IN.PACT AV DCB) is a PTA balloon catheter that uses a drug-coated balloon to open a blocked or narrowed arteriovenous (AV) fistula .

Is the paclitaxel coated PTA balloon catheter safe?

This device was shown to be as safe and effective as standard angioplasty balloons with no drug coating.