What is Succinimide used for?
Succinimide anticonvulsants are mostly used to treat absence seizures.
Which is succinimide derivative?
Succinimides are cyclic imides that have pharmaceutical applications such as in the production of anticonvulsant drugs ethosuzimide and phensuximide.
What are examples of anticonvulsants?
Anticonvulsants used to treat bipolar disorder include:
- carbamazepine (Tegretol)
- divalproex sodium, valproic acid, or valproate sodium ( Depakote, Depakene )
- lamotrigine (Lamictal)
Which drug is used as anticonvulsant?
Summary of Antiepileptic Drugs
| Narrow-spectrum AEDs: | Broad-spectrum AEDs: |
|---|---|
| – carbamazepine (Tegretol) | – topiramate (Topamax) |
| – oxcarbazepine (Trileptal) | – zonisamide (Zonegran) |
| – gabapentin (Neurontin) | – levetiracetam (Keppra) |
| – pregabalin (Lyrica) | – clonazepam (Klonopin) |
How much water is required to dissolve a gram of Succinimide?
1g dissolves in 3ml water, 0.7ml boiling water, 24ml alcohol, and 5ml alcohol @ 60˚ C.
Is Succinimide acidic or basic?
The compound is classified as a cyclic imide….Succinimide.
| Names | |
|---|---|
| Melting point | 125 to 127 °C (257 to 261 °F; 398 to 400 K) |
| Boiling point | 287 to 289 °C (549 to 552 °F; 560 to 562 K) |
| Solubility in water | 0.33 g/mL |
| Acidity (pKa) | 9.5 |
How do Hydantoins work?
Hydantoins are a class of drugs mainly used to treat seizures (anticonvulsant or antiepileptic drugs). Hydantoins reduce seizures by targeting the sodium channel present throughout the nerves. Activation of sodium channels results in the conduction of electrical impulses and the release of neurotransmitters.
What class of drug is ethosuximide?
Ethosuximide is in a class of medications called anticonvulsants. It works by reducing abnormal electrical activity in the brain.
How do anticonvulsants work for pain?
Carbamazepine, the first anticonvulsant studied in clinical trials, probably alleviates pain by decreasing conductance in Na+ channels and inhibiting ectopic discharges. Results from clinical trials have been positive in the treatment of trigeminal neuralgia, painful diabetic neuropathy and postherpetic neuralgia.
Is succinimide acidic or basic?