What is the composition of surfactant?

Surfactant comprises 80% phosphatidylcholine (PC), of which dipalmitoyl-PC, palmitoyl-myristoyl-PC and palmitoyl-palmitoleoyl-PC together are 75%. Anionic phosphatidylglycerol and cholesterol are about 10% each, whereas surfactant proteins SP-A to -D comprise 2-5%.

What does alveolar fluid contain?

The fluid within the alveoli, often referred to as alveolar fluid, is part of the alveolar surface network (Scarpelli, 2003). This network within the alveoli can be envisaged as a foam made of surfactant and water. The foam forms a network within the alveoli and has a gas:fluid volume ratio of 900:1 (Scarpelli, 2003).

What do surfactants do in the lungs?

Surfactant is released from the lung cells and spreads across the tissue that surrounds alveoli. This substance lowers surface tension, which keeps the alveoli from collapsing after exhalation and makes breathing easy.

What is surfactant in respiratory system?

Abstract. Pulmonary surfactant is a surface active material able to reduce surface tension at the alveolar and bronchiolar air-liquid interface.

What is surfactant example?

Sodium stearate is a good example of a surfactant. It is the most common surfactant in soap. Other anionic surfactants include dioctyl sodium sulfosuccinate (DOSS), linear alkylbenzene sulfonates (LABs) and alkyl-aryl ether phosphates.

How do you get fluid out of alveoli?

Specialized coughing

  1. Inhale slowly, filling up as much of your lungs as you can.
  2. Hold your breath for three seconds.
  3. Exhale about one fourth of your air.
  4. Cough forcefully, blowing as much air as you can.
  5. Repeat for three cycles.

How do you remove water from your lungs?

Thoracentesis is a procedure to remove fluid or air from around the lungs. A needle is put through the chest wall into the pleural space. The pleural space is the thin gap between the pleura of the lung and of the inner chest wall.

Does surfactant prevent lung collapse?

It is established that pulmonary surfactant reduces surface tension at the air–water interface in the alveoli, thereby preventing collapse of these structures at end-expiration. In this manner, surfactant reduces the work associated with breathing.

What secretes surfactant in the lungs?

The pulmonary surfactant is produced by the alveolar type-II (AT-II) cells of the lungs. It is essential for efficient exchange of gases and for maintaining the structural integrity of alveoli. Surfactant is a secretory product, composed of lipids and proteins.

Where does the fluid in the respiratory tract come from?

Respiratory tract fluid, produced from an enormous area spanning the mucosa of the nose to the alveolar surface, is a complex mixture of serum transudate and locally secreted proteins and glycomucoproteins and of inflammatory and immune effector cells intermingled.

How much fluid is in the developing lung?

Fetal lung fluid is a product of the epithelial lining of the developing lung (Wilson et al., 2007; Helve et al., 2009 ), averaging 4–6 mL/kg per hour.

How is fluid drained from the pleura of the lung?

How you have pleurodesis. There are different ways of having this treatment, depending on whether you need to have fluid drained beforehand. If you have no fluid to be drained, your doctor might put a thorascope into your chest until it is between the coverings of the lung (the pleura).

Is it dangerous to have fluid around the lung?

Fluid around the lung (pleural effusion) is a potentially dangerous condition that can masquerade as something less worrisome. What may seem like chest pain or coughing due to a bad cold could actually have serious health ramifications. It’s not that rare, either.