What cells express ICAM-1?

The intercellular adhesion molecule-1 (ICAM1/CD54), a transmembrane glycoprotein belonging to the immunoglobulin (Ig) superfamily, is expressed by several cell types including leucocytes, fibroblasts, and endothelial cells17.

What does ICAM 2 do?

ICAM-2 molecules regulate spermatid adhesion on Sertoli cell on the apical side of the blood-testis barrier (towards the lumen), thus playing a major role in spermatogenesis. This protein may also play a role in lymphocyte recirculation by blocking LFA-1-dependent cell adhesion.

What is VCAM ICAM?

In molecular biology, intercellular adhesion molecules (ICAMs) and vascular cell adhesion molecule-1 (VCAM-1) are part of the immunoglobulin superfamily. They are important in inflammation, immune responses and in intracellular signalling events. The ICAM family consists of five members, designated ICAM-1 to ICAM-5.

What does ICAM mean?


Acronym Definition
ICAM Integrated Computer Aided Manufacturing
ICAM Integrated Computer-Aided Manufacturing
ICAM Improved Chemical Agent Monitor
ICAM Interdisciplinary Center for Applied Mathematics

Is ICAM-1 an integrin?

ICAM-1 is a ligand for LFA-1 (integrin), a receptor found on leukocytes. When activated, leukocytes bind to endothelial cells via ICAM-1/LFA-1 and then transmigrate into tissues.

What does ICAM stand for in sales?


Acronym Definition
ICAM Identity, Credential and Access Management (cyber security; identity management)
ICAM International Conference and Annual Meeting (business management)
ICAM International Confederation of Architectural Museums
ICAM Integrated Computer Aided Manufacturing

What does VLA-4 do?

The integrin VLA-4 is expressed on the cell surfaces of stem cells, progenitor cells, T and B cells, monocytes, natural killer cells, eosinophils, and neutrophils. It functions to promote an inflammatory response by the immune system by assisting in the movement of leukocytes to tissue that requires inflammation.