What cells express ICAM-1?
The intercellular adhesion molecule-1 (ICAM1/CD54), a transmembrane glycoprotein belonging to the immunoglobulin (Ig) superfamily, is expressed by several cell types including leucocytes, fibroblasts, and endothelial cells17.
What does ICAM 2 do?
ICAM-2 molecules regulate spermatid adhesion on Sertoli cell on the apical side of the blood-testis barrier (towards the lumen), thus playing a major role in spermatogenesis. This protein may also play a role in lymphocyte recirculation by blocking LFA-1-dependent cell adhesion.
What is VCAM ICAM?
In molecular biology, intercellular adhesion molecules (ICAMs) and vascular cell adhesion molecule-1 (VCAM-1) are part of the immunoglobulin superfamily. They are important in inflammation, immune responses and in intracellular signalling events. The ICAM family consists of five members, designated ICAM-1 to ICAM-5.
What does ICAM mean?
ICAM
| Acronym | Definition |
|---|---|
| ICAM | Integrated Computer Aided Manufacturing |
| ICAM | Integrated Computer-Aided Manufacturing |
| ICAM | Improved Chemical Agent Monitor |
| ICAM | Interdisciplinary Center for Applied Mathematics |
Is ICAM-1 an integrin?
ICAM-1 is a ligand for LFA-1 (integrin), a receptor found on leukocytes. When activated, leukocytes bind to endothelial cells via ICAM-1/LFA-1 and then transmigrate into tissues.
What does ICAM stand for in sales?
ICAM
| Acronym | Definition |
|---|---|
| ICAM | Identity, Credential and Access Management (cyber security; identity management) |
| ICAM | International Conference and Annual Meeting (business management) |
| ICAM | International Confederation of Architectural Museums |
| ICAM | Integrated Computer Aided Manufacturing |
What does VLA-4 do?
The integrin VLA-4 is expressed on the cell surfaces of stem cells, progenitor cells, T and B cells, monocytes, natural killer cells, eosinophils, and neutrophils. It functions to promote an inflammatory response by the immune system by assisting in the movement of leukocytes to tissue that requires inflammation.